Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length481 amino acids

Chemical FormulaC2399H3772N640O668S13

DescriptionStandard

        MGAQSLAVACGALALCLALTTAANPGFVVRITQAGLDYAHQHGITVLEKELAELTLPDISGNFRIWHVGKVQYEISRLSLHSFHLPYSRISLVPGVGLQVSISNAFAELDGNWRVKMHFIRDHGSFDLRVENVYIKIHLRLGSSTSGKPTIDTSSCSTRISNVRVHFSGKFGWLYNLFHKAVESRFRKILESKVCESVAKSVRSELQPYAQTLPVTAKIDAMAGIDYSLVAPPTVTAQSLDVDLKGEFFSLAHRSAVPFPPLALALPPDHDRMVYFGASSYFFNTASFAYHAAGALVFEITNSVIPKGVEFQLNTSTFSAFIPQLENMYPHMEMKVRLSAPSAPFLTIGPDGLSLKPVVDIQTYAILPNSTLAPLFLLSLTGNVSAVIDVKSGHIVGSLKVGRLKLSLKHSDVGTFQVRMLQSIMNVLASNILLPRLNERLAEGFPLPLPDRIQLSNILVGFHQNFLLLGADVQYHPQGPR
    

Molecular Weight52684.34 Da

Isoelectric Point (pI)9.01

Net Charge (pH 7.0)7.07

Net Charge (pH 7.4) 5.79

Charge Density (pH 7.0) 0.0147

GRAVY Index0.19

Hydrophobic Moment 0.72

Boman Index0.16

Instability Index32.49

Aliphatic Index 103.78

Aromaticity 0.0894

Extinction Coeff. Reduced 35870.00

Extinction Coeff. Oxidized 36120.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0077454 VERIFIED: NO

Provenance & Taxonomy

OrganismAmazona collaria [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria