Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length446 amino acids

Chemical FormulaC2212H3554N560O628S17

DescriptionStandard

        MFLWCVLVLVSLLSVATGTSAGVKARITQKGLEYAYSKSFSDIPDRMQIVNLGLPKSALRLVPGTGVMLSVGDAYISLRGNWRVKYSWIIKASGSFELAVSELAISTTIAVKSDVTGRPTVSVTKCEATVGSVKVRFHGGASWLYNLFDSFINKDLRNALQKQICPLVTASIAEMNKTLKTLNVLAKVDQYAELEYSMVESPVISNAMIDLGLKGEFFNIGQHEEPPFSPRPFLLPSQDTNMLYIGVSAFSINSAGFVYHRAGALRLYITDGMIPSGSLNRLNTKTFGKFIPQIAKMSPGLMMKLLVETVKEPIITLEPNNMTVQASSKVTAYAIQPNSILSPLFVLKLEASVSAHIYVTGLKLAGHVTLNKIDMSLAESYVGPFQVKSLEDIFTTVVKDVIIPKVNAGVKEGYPLPAIGKMQLVKSQLQVLKDYLLIGTDVKFTG
    

Molecular Weight48586.36 Da

Isoelectric Point (pI)9.31

Net Charge (pH 7.0)10.93

Net Charge (pH 7.4) 10.30

Charge Density (pH 7.0) 0.0245

GRAVY Index0.25

Hydrophobic Moment 0.69

Boman Index0.17

Instability Index29.66

Aliphatic Index 106.84

Aromaticity 0.0830

Extinction Coeff. Reduced 44350.00

Extinction Coeff. Oxidized 44475.00

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Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0365069 VERIFIED: NO

Provenance & Taxonomy

OrganismSinocyclocheilus anshuiensis [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria