Peptide Database

Peptide NameCryptdin-3

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Standard StatusStandard

Sequence Length22 amino acids

Chemical FormulaC111H187N39O30S4

DescriptionStandard

        RDLICLCRKRRCNRGELFYGTC
    

Molecular Weight2676.18 Da

Isoelectric Point (pI)9.30

Net Charge (pH 7.0)3.72

Net Charge (pH 7.4) 3.46

Charge Density (pH 7.0) 0.1692

GRAVY Index-0.50

Hydrophobic Moment 0.39

Boman Index-0.39

Instability Index58.97

Aliphatic Index 70.91

Aromaticity 0.0909

Extinction Coeff. Reduced 1490.00

Extinction Coeff. Oxidized 1740.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1168.09

LogP -12.02

H-bond Donors 48.0

H-bond Acceptors 38.0

Rotatable Bonds 91.0

Heavy Atoms 184.0

Ring Count 2.0

Amide Bonds 22.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0227184 VERIFIED: YES

Provenance & Taxonomy

Organismnot reported [other]

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Anti-Gram-negative

TargetEscherichia coli TOP10

MethodMex pooled growth assay (OD_ID at 4.5 h; Wald adjusted p-value)