Peptide Database

Peptide NameLantibiotic

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length58 amino acids

Chemical FormulaC240H395N69O84S7

DescriptionStandard

        MANNLFDLDVQVNKSQGSVEPQVLSIVACSSGCGSGKTAASCVATCGNKCFTNVGSLC
    

Molecular Weight5815.57 Da

Isoelectric Point (pI)5.86

Net Charge (pH 7.0)-0.56

Net Charge (pH 7.4) -0.87

Charge Density (pH 7.0) -0.0096

GRAVY Index0.31

Hydrophobic Moment 0.45

Boman Index0.15

Instability Index36.38

Aliphatic Index 77.24

Aromaticity 0.0345

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 375.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 2470.44

LogP -37.48

H-bond Donors 89.0

H-bond Acceptors 91.0

Rotatable Bonds 193.0

Heavy Atoms 400.0

Ring Count 3.0

Amide Bonds 65.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0336922 VERIFIED: NO

Provenance & Taxonomy

OrganismPaenibacillus terrae [Bacterium]

FamilyLantibiotic

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Bacteriocin Lantibiotic Anti-Gram-positive Non-hemolytic Non-ribosomal

TargetGram-positive bacteria

MethodQualitative functional evidence