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MYP_083870
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Basic Information
Hylaranin-L1
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antifungal
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Standard
18 amino acids
C88H151N21O21S
Standard
Sequence
GVLSAFKNALPGIMKIIV
Physicochemical Analysis
1871.33 Da
10.00
1.76
1.55
0.0977
1.29
0.60
0.48
-2.36
151.67
0.0556
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
664.59
-2.89
22.0
24.0
62.0
131.0
2.0
18.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0327886 VERIFIED: YES
Provenance & Taxonomy
Hylarana latouchii [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal
Escherichia coli NCTC 10418
128 μg/mL
MBC
PMID24378871 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/24378871/
RECORD: Rec_0333477 VERIFIED: YES
Provenance & Taxonomy
Hylarana latouchii [Animal]
156873
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
C-terminal NH2
Bio-Activity Profile
Antimicrobial Antifungal
Escherichia coli
34 μM
MIC
PaperHylaranins: prototypes of a new class of amphibian antimicrobial peptide from the skin secretion of the oriental broad-folded frog, Hylarana latouchii.
RECORD: Rec_0340480 VERIFIED: YES
Provenance & Taxonomy
Hylarana latouchii,Sylvirana latouchii [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Hemolytic Anti-Gram-positive
Staphylococcus aureus
4.3 μM
MIC
RECORD: Rec_0346249 VERIFIED: YES
Provenance & Taxonomy
Hylarana latouchii,Sylvirana latouchii [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Hemolytic Anti-Gram-negative
Escherichia coli
34.2 μM
MIC
RECORD: Rec_0358959 VERIFIED: YES
Provenance & Taxonomy
Hylarana latouchii [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal
Candida albicans NCPF 1467
16 μg/mL
MIC
PMID24378871 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/24378871/
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