Peptide Database

Peptide NameEnzyme inhibitor 12

Function Ontology

Enzyme modulation ▸ Enzyme inhibition ▸ ACE inhibition ▸ ACE inhibitory

Other / Curated residual function label ▸ Generic enzyme inhibition annotation

Standard StatusStandard

Sequence Length7 amino acids

Chemical FormulaC35H59N7O10

DescriptionStandard

        TPITPLP
    

Molecular Weight737.88 Da

Isoelectric Point (pI)5.18

Net Charge (pH 7.0)-0.60

Net Charge (pH 7.4) -0.79

Charge Density (pH 7.0) -0.0860

GRAVY Index0.30

Hydrophobic Moment 0.31

Boman Index0.39

Instability Index36.09

Aliphatic Index 111.43

Aromaticity 0.0000

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 0.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 252.01

LogP -1.32

H-bond Donors 7.0

H-bond Acceptors 10.0

Rotatable Bonds 16.0

Heavy Atoms 52.0

Ring Count 3.0

Amide Bonds 6.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0247886 VERIFIED: YES

Provenance & Taxonomy

OrganismHordeum vulgare [Plant]

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Enzyme inhibitory ACE inhibitory

TargetAngiotensin-I converting enzyme

Activity133.95±4.35 μM

MethodIC50