Peptide Database

Peptide NameEndolysin (EC 4.2.2.n2) (Lysis protein) (Lysozyme) (Transglycosylase)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Bacteriolytic activity ▸ Bacteriolytic enzyme

Enzyme / Catalytic activity ▸ Lyase

Toxicity / Safety ▸ Cytolysis / cell lysis ▸ Cytolytic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length153 amino acids

Chemical FormulaC761H1168N214O219S4

DescriptionStandard

        MPRSDCHPQVAAFLDMIAFSEGTRGRGDDGYNKLVNPAGFFDSYATHPNVLVQVNPTLKSTAAGRYQFLSKHWAHYRDQLGLPDFGPESQDAWAIQLIRERKTLDDVLKGRIPQAVAKCTNIWASLPGAGYGQREHKLADLLTKFTEFGGVLA
    

Molecular Weight16946.98 Da

Isoelectric Point (pI)7.82

Net Charge (pH 7.0)0.93

Net Charge (pH 7.4) 0.40

Charge Density (pH 7.0) 0.0061

GRAVY Index-0.37

Hydrophobic Moment 0.62

Boman Index0.01

Instability Index29.05

Aliphatic Index 76.60

Aromaticity 0.1046

Extinction Coeff. Reduced 23950.00

Extinction Coeff. Oxidized 24075.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 6925.01

LogP -67.54

H-bond Donors 239.0

H-bond Acceptors 229.0

Rotatable Bonds 548.0

Heavy Atoms 1198.0

Ring Count 33.0

Amide Bonds 165.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0210224 VERIFIED: YES

Provenance & Taxonomy

OrganismAeromonas phage PAS-1 [Virus]

FamilyGlycosyl hydrolase 24

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Bacteriolytic enzyme Lyase Cytolytic Non-hemolytic