Peptide Database

Peptide NameBeta-defensin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length114 amino acids

Chemical FormulaC599H929N165O167S8

DescriptionStandard

        MLIILVLELKTYPTHLFPAAGWEVKRCWKDNIGHCRKRCFHVERYKLLCMNKLTCCIPIKEDDGYTKTPPRPVPFEEQITVNTNDWDLFSNSPISWFDDEVTRPTSARSRSRGP
    

Molecular Weight13370.31 Da

Isoelectric Point (pI)8.57

Net Charge (pH 7.0)2.72

Net Charge (pH 7.4) 2.23

Charge Density (pH 7.0) 0.0238

GRAVY Index-0.51

Hydrophobic Moment 0.56

Boman Index-0.09

Instability Index56.28

Aliphatic Index 72.63

Aromaticity 0.1053

Extinction Coeff. Reduced 26470.00

Extinction Coeff. Oxidized 26845.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 5323.06

LogP -45.76

H-bond Donors 191.0

H-bond Acceptors 181.0

Rotatable Bonds 428.0

Heavy Atoms 939.0

Ring Count 29.0

Amide Bonds 119.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0244256 VERIFIED: NO

Provenance & Taxonomy

OrganismFelis catus [Animal]

FamilyDefensin

Tax ID9685

Structure & Mods

Configlinear polypeptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Defensin Non-hemolytic

MethodQualitative functional evidence