Peptide Database

Peptide NameBeta-defensin 42 (BD-42) (mBD-42) (Defensin; beta 42)

Function Ontology

Antimicrobial

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length75 amino acids

Chemical FormulaC370H587N95O100S10

DescriptionStandard

        MNLRLSCLLFILVTSLPAGRCSIGNKGISFETCTAIEGLCFFGCKLGWVWIAYCNNIMSCCRKDTDFVLPQTKGI
    

Molecular Weight8286.84 Da

Isoelectric Point (pI)8.49

Net Charge (pH 7.0)2.42

Net Charge (pH 7.4) 2.08

Charge Density (pH 7.0) 0.0323

GRAVY Index0.59

Hydrophobic Moment 0.52

Boman Index0.23

Instability Index51.20

Aliphatic Index 98.80

Aromaticity 0.1067

Extinction Coeff. Reduced 12490.00

Extinction Coeff. Oxidized 12990.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3107.68

LogP -26.36

H-bond Donors 117.0

H-bond Acceptors 113.0

Rotatable Bonds 271.0

Heavy Atoms 575.0

Ring Count 12.0

Amide Bonds 79.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0129835 VERIFIED: YES

Provenance & Taxonomy

OrganismMus musculus [Animal]

FamilyBeta-defensin; Defensin

Tax ID10090

Structure & Mods

Configdisulfide-constrained cyclic peptide [Cyclic]

Chiralitycanonical L-amino-acid peptide [L]

Disulfidedisulfide bond; sites not specified

Bio-Activity Profile

Function

Antimicrobial Defensin Non-hemolytic