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MYP_083777
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Basic Information
Human cFos (139-164)
Anticancer
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Delivery / Targeting ▸ Cell penetration ▸ Cell-penetrating peptide
Delivery / Targeting ▸ Drug delivery vehicle
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Standard
28 amino acids
C136H250N60O40S2
Standard
Sequence
KRRIRRERNKMAAAKSRNRRRELTDTGC
Physicochemical Analysis
3429.95 Da
11.91
8.75
8.53
0.3126
-1.94
0.61
-0.92
134.91
38.57
0.0000
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1742.95
-23.58
68.0
51.0
126.0
238.0
0.0
29.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0210000 VERIFIED: YES
Provenance & Taxonomy
Synthetic construct [Synthetic]
Protein-derived CPP
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Cell-penetrating peptide
RAW 264.7
Fluorescence-based uptake assay
PMID11084031 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/11084031/
RECORD: Rec_0253027 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
C-terminal Gly Cys amide labelled with fluorescein
Bio-Activity Profile
Drug Delivery Vehicle Cell-penetrating peptide
PaperCPPsite: a curated database of cell penetrating peptides PMID22403286 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/22403286/
RECORD: Rec_0351472 VERIFIED: YES
Provenance & Taxonomy
Homo sapiens [Animal]
Human
9606
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Cell-penetrating peptide Cargo delivery
PMID11084031 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/11084031/
RECORD: Rec_0422620 VERIFIED: YES
Provenance & Taxonomy
Protein derived [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Conjugation with Alexa 488 at glycyl cysteine sequence
Bio-Activity Profile
Antimicrobial Anticancer
Not available
PMID19707187 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/19707187/
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