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MYP_083761
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Basic Information
Polybia-MPI peptide
Anticancer
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antibiotic activity
Antimicrobial ▸ Antifungal
Hormonal / Endocrine ▸ Hormone peptide
Immunology ▸ Immune cell migration ▸ Chemotactic peptide
Immunology ▸ Immune modulation ▸ Immunomodulatory activity
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Toxic
Standard
14 amino acids
C78H131N19O20
Standard
Sequence
IDWKKLLDAAKQIL
Physicochemical Analysis
1654.99 Da
8.50
0.76
0.55
0.0542
0.06
0.71
0.06
33.86
153.57
0.0714
5500.00
5500.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
653.16
-1.70
22.0
21.0
58.0
117.0
2.0
14.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0000400 VERIFIED: NO
Provenance & Taxonomy
Polybia paulista [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Hormone
Bacillus subtilis, Staphylococcus aureus and, Escherichia coli, Pseudomonas aeruginosa
RECORD: Rec_0013697 VERIFIED: YES
Provenance & Taxonomy
Polybia paulista [Animal]
Structure & Mods
topology not specified [Not included yet]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Anti-Gram-positive Anti-Gram-negative
Escherichia coli
5 μM
MIC
PaperPubMed PMID: 19463874 PMID19463874 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/19463874/
RECORD: Rec_0021488 VERIFIED: YES
Provenance & Taxonomy
Polybia paulista [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antifungal Anticancer
Staphylococcus aureus
9 μM
MIC
PaperStructural and functional characterization of two novel peptide toxins isolated from the venom of the social wasp Polybia paulista
RECORD: Rec_0022018 VERIFIED: NO
Provenance & Taxonomy
Social wasp [Animal]; Insecta [Animal]
33208; 50557
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Anticancer
PaperAPD2: the updated antimicrobial peptide database and its application in peptide design PMID18957441 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/18957441/
RECORD: Rec_0052368 VERIFIED: NO
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Anticancer
PaperAntiCP 2.0: an updated model for predicting anticancer peptides (benchmark provenance; exact sequence-level experiment paper unresolved here) | https://pubmed.ncbi.nlm.nih.gov/32770192/
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