Peptide Database

Peptide NameBeta-defensin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length95 amino acids

Chemical FormulaC473H760N126O137S9

DescriptionStandard

        MKLFLVFMVLLFEVPQDRAWPKKCFNNVSGFCRKRCKLGEISEMGCLSGKLCCVNEGENRKYLEAQKPPAQTADKSAEVQDYIALPTTTLLTTAQ
    

Molecular Weight10692.44 Da

Isoelectric Point (pI)8.57

Net Charge (pH 7.0)2.45

Net Charge (pH 7.4) 2.12

Charge Density (pH 7.0) 0.0258

GRAVY Index-0.18

Hydrophobic Moment 0.57

Boman Index-0.01

Instability Index24.27

Aliphatic Index 79.05

Aromaticity 0.0842

Extinction Coeff. Reduced 8480.00

Extinction Coeff. Oxidized 8855.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 4255.91

LogP -39.22

H-bond Donors 150.0

H-bond Acceptors 149.0

Rotatable Bonds 359.0

Heavy Atoms 745.0

Ring Count 14.0

Amide Bonds 103.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0035937 VERIFIED: NO

Provenance & Taxonomy

OrganismOryctolagus cuniculus [Animal]

FamilyDefensin

Tax ID9986

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Defensin Non-hemolytic Non-ribosomal

MethodQualitative functional evidence