Peptide Database

Peptide NameSLAY-screened peptide P1442

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial

Standard StatusStandard

Sequence Length4 amino acids

Chemical FormulaC16H26N4O7

DescriptionStandard

        PPSS
    

Molecular Weight386.40 Da

Isoelectric Point (pI)5.96

Net Charge (pH 7.0)-0.04

Net Charge (pH 7.4) -0.10

Charge Density (pH 7.0) -0.0104

GRAVY Index-1.20

Hydrophobic Moment 0.10

Boman Index-0.03

Instability Index151.95

Aliphatic Index 0.00

Aromaticity 0.0000

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 0.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 168.30

LogP -3.23

H-bond Donors 6.0

H-bond Acceptors 7.0

Rotatable Bonds 8.0

Heavy Atoms 27.0

Ring Count 2.0

Amide Bonds 3.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0253464 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

Tax ID32630

Structure & Mods

Configlinear peptide [Linear]

Chiralitystereochemistry not specified [Other]

Bio-Activity Profile

Function

Antimicrobial Antibacterial

Targetrecombinant Escherichia coli surface-display screening

MethodSLAY screening

PaperAshley T Tucker, Sean P Leonard, Cory D DuBois, Gregory A Knauf, Ashley L Cunningham, Claus O Wilke, M Stephen Trent, Bryan W Davies. Discovery of Next-Generation Antimicrobials through Bacterial Self-Screening of Surface-Displayed Peptide Libraries. Cell. 2018 Jan 25;172(3):618-628.e13. doi: 10.1016/j.cell.2017.12.009. Epub 2018 Jan 4. PMID29307492 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/29307492/

RECORD: Rec_0305414 VERIFIED: NO

Provenance & Taxonomy

OrganismBarbus barbus [Animal]

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibacterial

TargetMicrococcus luteus