Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length177 amino acids

Chemical FormulaC891H1411N231O237S8

DescriptionStandard

        PTALPTAHKPMLLLAVTEVVTSSAAFTYFMAGALRRNISSDMLPQKFPLQLKTKSMGVFTPQLQELYPDQPMELHLWARQQPLLSCQPHALHGTLFGSVEAFVVLPNATRVPAFLLDIDANVTGKPTITRNRLGGTVKLTGGLLVPQVKKLETLLKFGLWLFGVPWANSECCPHPVP
    

Molecular Weight19407.66 Da

Isoelectric Point (pI)9.35

Net Charge (pH 7.0)5.38

Net Charge (pH 7.4) 4.99

Charge Density (pH 7.0) 0.0304

GRAVY Index0.16

Hydrophobic Moment 0.54

Boman Index0.17

Instability Index47.13

Aliphatic Index 99.15

Aromaticity 0.0791

Extinction Coeff. Reduced 19480.00

Extinction Coeff. Oxidized 19605.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 7299.86

LogP -75.01

H-bond Donors 248.0

H-bond Acceptors 255.0

Rotatable Bonds 614.0

Heavy Atoms 1367.0

Ring Count 40.0

Amide Bonds 190.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0132416 VERIFIED: NO

Provenance & Taxonomy

OrganismHemiprocne comata [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria