Peptide Database

Peptide NameSLAY-screened peptide P1652

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial

Standard StatusStandard

Sequence Length20 amino acids

Chemical FormulaC94H151N23O26S4

DescriptionStandard

        ICFTMSIRCTPGFLCSTIGP
    

Molecular Weight2147.60 Da

Isoelectric Point (pI)7.97

Net Charge (pH 7.0)0.73

Net Charge (pH 7.4) 0.48

Charge Density (pH 7.0) 0.0365

GRAVY Index1.00

Hydrophobic Moment 0.34

Boman Index0.36

Instability Index47.77

Aliphatic Index 78.00

Aromaticity 0.1000

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 125.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 761.69

LogP -7.51

H-bond Donors 30.0

H-bond Acceptors 31.0

Rotatable Bonds 64.0

Heavy Atoms 147.0

Ring Count 4.0

Amide Bonds 19.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0344190 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

Tax ID32630

Structure & Mods

Configlinear peptide [Linear]

Chiralitystereochemistry not specified [Other]

Bio-Activity Profile

Function

Antimicrobial Antibacterial

Targetrecombinant Escherichia coli surface-display screening

MethodSLAY screening

PaperAshley T Tucker, Sean P Leonard, Cory D DuBois, Gregory A Knauf, Ashley L Cunningham, Claus O Wilke, M Stephen Trent, Bryan W Davies. Discovery of Next-Generation Antimicrobials through Bacterial Self-Screening of Surface-Displayed Peptide Libraries. Cell. 2018 Jan 25;172(3):618-628.e13. doi: 10.1016/j.cell.2017.12.009. Epub 2018 Jan 4. PMID29307492 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/29307492/