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MYP_083673
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Basic Information
Bac5 258
Anticancer
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Standard
17 amino acids
C105H165N35O19
Standard
Sequence
RFRPPIRRPPIRPPFYR
Physicochemical Analysis
2221.66 Da
12.00
5.76
5.55
0.3388
-1.37
0.47
-0.53
131.64
45.88
0.1765
1490.00
1490.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
867.81
-4.70
31.0
25.0
61.0
159.0
9.0
16.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0004292 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Escherichia coli BW25113
8 μM
MIC
PMID31692278 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/31692278/
RECORD: Rec_0086468 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Escherichia coli EURL-VTEC C07 STEC:O157
64 μM
MIC
PMID31692278 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/31692278/
RECORD: Rec_0094633 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Staphylococcus aureus ATCC 25923
64 μM
MIC
PMID31692278 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/31692278/
RECORD: Rec_0125086 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Anticancer
MEC-1
5 %
Cytotoxicity
PaperProline-Rich Peptides with Improved Antimicrobial Activity against E. coli, K. pneumoniae, and A. baumannii. ChemMedChem. 2019 Dec 17;14(24):2025-2033. doi: 10.1002/cmdc.201900465. PMID: 31692278. PMID31692278 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/31692278/
RECORD: Rec_0135682 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Acinetobacter baumannii ATCC 19606
64 μM
MIC
PMID31692278 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/31692278/
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