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MYP_083668
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Basic Information
Brevinin-1-AJ1
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antifungal
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Standard
24 amino acids
C130H214N28O29S2
Standard
Sequence
FLSTLLKVAFKVVPTLFCPITKKC
Physicochemical Analysis
2697.39 Da
9.70
3.74
3.50
0.1557
1.07
0.55
0.31
8.76
121.67
0.1250
0.00
125.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
900.04
-2.98
33.0
35.0
86.0
189.0
5.0
23.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0043231 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Brevinin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
-
Escherichia coli TOP10
Mex pooled growth assay (OD_ID at 4.5 h; Wald adjusted p-value)
PaperKoch P, Schmitt S, Cardner M, Beerenwinkel N, Panke S, Held M. Discovery of antimicrobials by massively parallelized growth assays (Mex). Scientific Reports. 2022;12:4097. doi:10.1038/s41598-022-07755-7 PMID35260685 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/35260685/
RECORD: Rec_0058411 VERIFIED: YES
Provenance & Taxonomy
Amolops jingdongensis [Animal]
Brevinin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
18-24
Bio-Activity Profile
Antimicrobial Antifungal
Staphylococcus aureus ATCC 2592
1.17 μg/mL
MIC
PaperAntimicrobial peptide diversity in the skin of the torrent frog, Amolops jingdongensis
RECORD: Rec_0063458 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide; DSSP H 33.3%, E 0.0%, T 37.5%, C 29.2% [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antibacterial Antimicrobial Antifungal
PaperAPD2: the updated antimicrobial peptide database and its application in peptide design PMID18957441 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/18957441/
RECORD: Rec_0076673 VERIFIED: YES
Provenance & Taxonomy
Amolops jingdongensis [Animal]
Brevinin
Structure & Mods
Single-chain peptide backbone represented as a linear sequence entry [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal
Bacillus subtilis ATCC 6633
4.7 μg/mL
MIC
PMID22828809 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/22828809/
RECORD: Rec_0183774 VERIFIED: YES
Provenance & Taxonomy
Amolops jingdongensis [Animal]
Brevinin
Structure & Mods
Single-chain peptide backbone represented as a linear sequence entry [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal
Candida albicans ATCC 2002
4.7 μg/mL
MIC
PMID22828809 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/22828809/
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