Peptide Database

Peptide NameGastrin

Function Ontology

Gastrointestinal bioactivity

Hormonal / Endocrine ▸ Hormone peptide

Neurological / Signaling ▸ Neuropeptide activity ▸ Neuropeptide

Standard StatusStandard

Sequence Length52 amino acids

Chemical FormulaC278H410N74O80S2

DescriptionStandard

        DLLEALSQDQKLLMAKFLPHIYAELANREGNWHEDAALRPLHDHDYPGWMDF
    

Molecular Weight6132.81 Da

Isoelectric Point (pI)4.79

Net Charge (pH 7.0)-5.88

Net Charge (pH 7.4) -6.30

Charge Density (pH 7.0) -0.1130

GRAVY Index-0.59

Hydrophobic Moment 0.44

Boman Index0.01

Instability Index54.55

Aliphatic Index 86.54

Aromaticity 0.1154

Extinction Coeff. Reduced 13980.00

Extinction Coeff. Oxidized 13980.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 2449.24

LogP -15.95

H-bond Donors 81.0

H-bond Acceptors 80.0

Rotatable Bonds 197.0

Heavy Atoms 434.0

Ring Count 15.0

Amide Bonds 55.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0103674 VERIFIED: YES

Provenance & Taxonomy

Organismnot reported [other]

FamilyGastrin/cholecystokinin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

C-TermAmidation

Bio-Activity Profile

Function

Hormone Gastrointestinal Neuropeptide

RECORD: Rec_0185198 VERIFIED: YES

Provenance & Taxonomy

Organismnot reported [other]

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Neuropeptide

Paper数据库级溯源文献：Wang Y, Wang M, Yin S, et al. NeuroPep: a comprehensive resource of neuropeptides. Database (Oxford). 2015:bav038. PMID 25931458; Bin Y, Zhang W, Tang W, et al. Prediction of Neuropeptides from Sequence Information Using Ensemble Classifier and Hybrid Features. J Proteome Res. 2020;19(9):3732-3740. PMID 32786686. PMID25931458;32786686 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/25931458/

RECORD: Rec_0360454 VERIFIED: YES

Provenance & Taxonomy

OrganismTrachemys scripta [Animal]

FamilyGastrin/cholecystokinin-like peptide

Tax ID34903

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Hormone Endocrine

Half-LifeMammalian: 1.1 hour; Yeast: 3 min; E. coli: >10 hour