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MYP_083647
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Basic Information
Unnamed
Anticancer
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Standard
29 amino acids
C145H260N66O41S
Standard
Sequence
RRRRRRRRGEDIIRNIARHLAQVGDSMDR
Physicochemical Analysis
3616.10 Da
12.00
6.85
6.60
0.2363
-1.67
0.90
-0.84
173.59
70.69
0.0000
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1843.31
-22.85
71.0
50.0
130.0
253.0
1.0
30.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0162472 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
mixed L/D amino-acid peptide [Mixed]
None
None
rrrrrrrr=D-isomer homopolymer of eight arginine residues
Bio-Activity Profile
Antimicrobial Anticancer
(68% apoptosis at 50 μM)
PaperPubMed PMID: 16568093 PMID16568093 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/16568093/
RECORD: Rec_0164229 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Synthetic peptide
32630
Structure & Mods
synthetic linear peptide [Linear]
mixed L/D amino-acid peptide [Mixed]
None
None
Bio-Activity Profile
Anticancer
NGP
10 μM
Concentration response
PaperBH3 peptidomimetics potently activate apoptosis and demonstrate single agent efficacy in neuroblastoma PMID16568093 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/16568093/
RECORD: Rec_0184598 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
mixed L/D amino-acid peptide [Mixed]
None
None
rrrrrrrr=D-isomer homopolymer of eight arginine residues
Bio-Activity Profile
Antimicrobial Anticancer
NGP (46% apoptosis at 20 μM)
PaperPubMed PMID: 16568093 PMID16568093 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/16568093/
RECORD: Rec_0236702 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Synthetic peptide
32630
Structure & Mods
synthetic linear peptide [Linear]
mixed L/D amino-acid peptide [Mixed]
None
None
Bio-Activity Profile
Anticancer
IMR5
20 μM
Concentration response
PaperBH3 peptidomimetics potently activate apoptosis and demonstrate single agent efficacy in neuroblastoma PMID16568093 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/16568093/
RECORD: Rec_0240781 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
mixed L/D amino-acid peptide [Mixed]
None
None
rrrrrrrr=D-isomer homopolymer of eight arginine residues
Bio-Activity Profile
Antimicrobial Anticancer
IMR-5 (35% apoptosis at 20 μM)
PaperPubMed PMID: 16568093 PMID16568093 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/16568093/
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