Peptide Database

Peptide NameKnot1 domain-containing protein

Function Ontology

Antimicrobial

Antimicrobial ▸ Antifungal

Antimicrobial ▸ Antifungal ▸ Fungicidal activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length78 amino acids

Chemical FormulaC360H589N107O108S10

DescriptionStandard

        MKLSPRLISTIPVLFMLLVATTGIGPVTVEARTCETSSQLFNGPCLSTTNCANVCHNEGFPDGDCRGFRRRCLCSRPC
    

Molecular Weight8464.83 Da

Isoelectric Point (pI)8.52

Net Charge (pH 7.0)2.52

Net Charge (pH 7.4) 2.13

Charge Density (pH 7.0) 0.0323

GRAVY Index0.12

Hydrophobic Moment 0.69

Boman Index0.04

Instability Index45.73

Aliphatic Index 77.44

Aromaticity 0.0513

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 500.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3424.45

LogP -41.44

H-bond Donors 128.0

H-bond Acceptors 122.0

Rotatable Bonds 270.0

Heavy Atoms 585.0

Ring Count 11.0

Amide Bonds 82.0

3D PDB MODEL

Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.

2D CHEMICAL STRUCTURE

Drag to move

Drag to move. Use the buttons to zoom.

RECORD: Rec_0404434 VERIFIED: NO

Provenance & Taxonomy

OrganismArabis alpina [Plant]

FamilyDefensin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antifungal Fungicide Non-hemolytic Non-ribosomal

MethodQualitative functional evidence