Peptide Database

Peptide NameChromogranin-A

Function Ontology

Hormonal / Endocrine ▸ Secretory pathway peptide ▸ Secretory granule peptide

Neurological / Signaling ▸ Neuropeptide activity ▸ Neuropeptide precursor

Standard StatusStandard

Sequence Length431 amino acids

Chemical FormulaC2057H3264N604O718S9

DescriptionStandard

        LPVNSPMNKGDTEVMKCIVEVISDTLSKPSPMPVSKECFETLRGDERILSILRHQNLLKELQDLALQGAKERTHQQKKHSSYEDELSEVLEKPNDQAEPKEVTEEVSSKDAAEKRDDFKEVEKSDEDSDGDRPQASPGLGPGPKVEEDNQAPGEEEEAPSNAHPLASLPSPKYPGPQAKEDSEGPSQGPASREKGLSAEQGRQTEREEEEEKWEEAEAREKAVPEEESPPTAAFKPPPSLGNKETQRAAPGWPEDGAGKMGAEEAKPPEGKGEWAHSRQEEEEMARAPQVLFRGGKSGEPEQEEQLSKEWEDAKRWSKMDQLAKELTAEKRLEGEEEEEEDPDRSMRLSFRARGYGFRGPGLQLRRGWRPNSREDSVEAGLPLQVRGYPEEKKEEEGSANRRPEDQELESLSAIEAELEKVAHQLEELRRG
    

Molecular Weight48232.13 Da

Isoelectric Point (pI)4.69

Net Charge (pH 7.0)-39.52

Net Charge (pH 7.4) -40.27

Charge Density (pH 7.0) -0.0917

GRAVY Index-1.33

Hydrophobic Moment 0.80

Boman Index-0.29

Instability Index75.94

Aliphatic Index 51.69

Aromaticity 0.0371

Extinction Coeff. Reduced 38960.00

Extinction Coeff. Oxidized 39085.00

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Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0159227 VERIFIED: NO

Provenance & Taxonomy

OrganismBos taurus [Animal]

FamilyChromogranin/secretogranin

Tax ID9913

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Other ModsSer81 Phosphoserine; Ser124 Phosphoserine; Tyr173 Phosphotyrosine; Ser182 Phosphoserine; Ser197 Phosphoserine; Ser277 Phosphoserine; Gly294 Amidation; Ser297 Phosphoserine; Ser307 Phosphoserine; Ser372 Phosphoserine; Ser376 Phosphoserine

Bio-Activity Profile

Function

Secretory granule peptide Neuropeptide precursor