Peptide Database

Peptide NameDEFENSIN domain-containing protein

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Antimicrobial ▸ Antifungal

Antimicrobial ▸ Antifungal ▸ Fungicidal activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length97 amino acids

Chemical FormulaC453H750N138O139S7

DescriptionStandard

        MRTLAILAAILLFALLAQAKSLQETADDAATQEQPGEDDQDLAVSFEENGLSTLRASGSQARIICLCRISRCSWPEAHFGRCTKKGRIAKLCCRRAP
    

Molecular Weight10578.10 Da

Isoelectric Point (pI)8.29

Net Charge (pH 7.0)1.55

Net Charge (pH 7.4) 1.17

Charge Density (pH 7.0) 0.0159

GRAVY Index-0.10

Hydrophobic Moment 0.66

Boman Index-0.05

Instability Index45.04

Aliphatic Index 90.82

Aromaticity 0.0412

Extinction Coeff. Reduced 5500.00

Extinction Coeff. Oxidized 5875.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 4490.89

LogP -50.09

H-bond Donors 164.0

H-bond Acceptors 149.0

Rotatable Bonds 358.0

Heavy Atoms 737.0

Ring Count 9.0

Amide Bonds 103.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0149140 VERIFIED: NO

Provenance & Taxonomy

OrganismMacaca mulatta [Animal]

FamilyDefensin

Tax ID9544

Structure & Mods

Configlinear polypeptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Defensin Antifungal Fungicide Non-hemolytic

MethodQualitative functional evidence