Peptide Database

Peptide NameBeta-defensin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length73 amino acids

Chemical FormulaC373H596N106O100S8

DescriptionStandard

        MRFAVLLFTIFFFMSQVLPVRGKFKEICERPNGSCRNFCIETEIHVGRCLNSRPCCLPLGNQPRIESTTPKKD
    

Molecular Weight8421.89 Da

Isoelectric Point (pI)9.15

Net Charge (pH 7.0)4.54

Net Charge (pH 7.4) 4.17

Charge Density (pH 7.0) 0.0622

GRAVY Index-0.10

Hydrophobic Moment 0.45

Boman Index-0.03

Instability Index56.71

Aliphatic Index 76.03

Aromaticity 0.0959

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 375.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3316.02

LogP -30.55

H-bond Donors 120.0

H-bond Acceptors 114.0

Rotatable Bonds 276.0

Heavy Atoms 587.0

Ring Count 14.0

Amide Bonds 78.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0355862 VERIFIED: NO

Provenance & Taxonomy

OrganismCallithrix jacchus [Animal]

FamilyDefensin

Tax ID9483

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Defensin Non-hemolytic Non-ribosomal

MethodQualitative functional evidence