Peptide Database

Peptide NameHistone H2A [Cleaved into: Acipensin 1 (Ac1); Acipensin 2 (Ac2); Acipensin 3 (Ac3); Acipensin 4 (Ac4); Acipensin 5 (Ac5); Acipensin 6 (Ac6)]

Function Ontology

Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive

Antimicrobial ▸ Antibiotic activity

Antimicrobial ▸ Antifungal

Antimicrobial ▸ Antifungal ▸ Anti-Candida

Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic

Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic

Venom / Toxin ▸ General toxin ▸ Cytotoxic

Standard StatusStandard

Sequence Length76 amino acids

Chemical FormulaC360H616N126O95S

DescriptionStandard

        MSGRGKTGGKARAKAKTRSSRAGLQFPVGRVHRLLRKGNYAQRVGAGAPVYLILELAGNAARDNKKTRIIPRHLQL
    

Molecular Weight8261.59 Da

Isoelectric Point (pI)12.00

Net Charge (pH 7.0)15.67

Net Charge (pH 7.4) 15.34

Charge Density (pH 7.0) 0.2062

GRAVY Index-0.57

Hydrophobic Moment 0.83

Boman Index-0.21

Instability Index45.03

Aliphatic Index 84.87

Aromaticity 0.0395

Extinction Coeff. Reduced 2980.00

Extinction Coeff. Oxidized 2980.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3634.83

LogP -41.57

H-bond Donors 132.0

H-bond Acceptors 114.0

Rotatable Bonds 285.0

Heavy Atoms 582.0

Ring Count 8.0

Amide Bonds 81.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0055442 VERIFIED: YES

Provenance & Taxonomy

OrganismAcipenser gueldenstaedtii [other]

FamilyHistone-derived

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibiotic Antifungal Anti-Candida Anti-Gram-negative Anti-Gram-positive Cytotoxic Hemolytic

TargetStaphylococcus aureus (Gram-positive)

RECORD: Rec_0235724 VERIFIED: YES

Provenance & Taxonomy

OrganismAcipenser gueldenstaedtii [other]

FamilyHistone-derived

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibiotic Antifungal Anti-Candida Anti-Gram-negative Anti-Gram-positive Cytotoxic Hemolytic

TargetEscherichia coli (Gram-negative)

RECORD: Rec_0235951 VERIFIED: YES

Provenance & Taxonomy

OrganismAcipenser gueldenstaedtii [other]

FamilyHistone-derived

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibiotic Antifungal Anti-Candida Anti-Gram-negative Anti-Gram-positive Cytotoxic Hemolytic

TargetListeria monocytogenes (Gram-positive)

RECORD: Rec_0253588 VERIFIED: YES

Provenance & Taxonomy

OrganismAcipenser gueldenstaedtii [other]

FamilyHistone-derived

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibiotic Antifungal Anti-Candida Anti-Gram-negative Anti-Gram-positive Cytotoxic Hemolytic

TargetCandida albicans