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MYP_083498
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Basic Information
Neuropeptide Y
Hormonal / Endocrine ▸ Hormone peptide
Metabolic ▸ Appetite and feeding regulation ▸ Feeding regulator
Neurological / Signaling ▸ Neuromodulation
Neurological / Signaling ▸ Neuropeptide activity ▸ Neuropeptide
Neurological / Signaling ▸ Neuropeptide Y family
Regulatory peptide ▸ Biological modulation
Regulatory peptide ▸ Biological regulation
Reproductive biology ▸ Reproductive modulation
Standard
36 amino acids
C188H283N53O58S
Standard
Sequence
YPSKPDSPGEDAPAEDMARYYSALRHYINLITRQRY
Physicochemical Analysis
4245.64 Da
6.76
-0.15
-0.42
-0.0042
-1.12
0.73
-0.23
82.09
54.44
0.1389
7450.00
7450.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1803.71
-17.42
63.0
60.0
131.0
300.0
10.0
37.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0015974 VERIFIED: YES
Provenance & Taxonomy
Nestor notabilis [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
-
Escherichia coli TOP10
Mex pooled growth assay (OD_ID at 4.5 h; Wald adjusted p-value)
PaperKoch P, Schmitt S, Cardner M, Beerenwinkel N, Panke S, Held M. Discovery of antimicrobials by massively parallelized growth assays (Mex). Scientific Reports. 2022;12:4097. doi:10.1038/s41598-022-07755-7 PMID35260685 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/35260685/
RECORD: Rec_0138853 VERIFIED: YES
Provenance & Taxonomy
Gallus gallus [Animal]
Neuropeptide Y
9031
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Bio-Activity Profile
Hormone Endocrine Neuropeptide Neuromodulator Metabolic regulation Physiological regulation Reproductive regulator Receptor modulation Feeding regulator
Mammalian: 2.8 hour; Yeast: 10 min; E. coli: 2 min
PaperSource-linked PubMed record(s) for Neuropeptide Y (Gallus gallus): PMID 1549597 PMID1549597 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/1549597/
RECORD: Rec_0172932 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Neuropeptide Y / neuropeptide F
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Bio-Activity Profile
Neuropeptide
Paper数据库级溯源文献：Wang Y, Wang M, Yin S, et al. NeuroPep: a comprehensive resource of neuropeptides. Database (Oxford). 2015:bav038. PMID 25931458; Bin Y, Zhang W, Tang W, et al. Prediction of Neuropeptides from Sequence Information Using Ensemble Classifier and Hybrid Features. J Proteome Res. 2020;19(9):3732-3740. PMID 32786686. PMID25931458;32786686 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/25931458/
RECORD: Rec_0254964 VERIFIED: NO
Provenance & Taxonomy
Gallus gallus [Animal]
NPY
9031
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Bio-Activity Profile
NPY-family Neuropeptide Neuromodulator
RECORD: Rec_0412686 VERIFIED: NO
Provenance & Taxonomy
Gallus gallus [Animal]
9031
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Hormone