Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length492 amino acids

Chemical FormulaC2412H3985N667O673S23

DescriptionStandard

        MSLFSWIIVVLLIATTSGVNPGVKVRLTAKGLEYGKVQVGMAAIQQNLRTIKIPDISGKKRISRIGKVKYRLSNMRILNVELPKSAVDPVPGTGVRLAMSNAKISMRGNWRVKKSGSFDLNVDRLGVSANIAIKSDSTGRPVVSTPSCSASVGSVRVKFRGGASWLYNLFNKFINKALRKAMQKQICPLVSRAISGVNPQLQTLNVLAKVDKLAEIDYSMTSSPTISKSSIDLNMKGEFYNIGRHQEPPFSPAAFSLPPQVNKMAYIGMSAFTANSAGFVYNRAGILTLNITDDMIPKSSPIRLNTRALGTFIPEIARRFPGLLVKMVVKTAKPPVITFQPNNATVQTIGTITAFAIQRNTTLSPLFVLNIDTSVSAKLSINGMKVVGKVSLNRLDLTMGTSSVGQFQVRALDNILEIVLRAVIIPLVNVKLSGGYPLPATGKMKLMNTDLQILKVRDDILCITRYMCWIYYITGILMRPEQSTQNIIVRMK
    

Molecular Weight53834.00 Da

Isoelectric Point (pI)10.47

Net Charge (pH 7.0)39.54

Net Charge (pH 7.4) 39.12

Charge Density (pH 7.0) 0.0804

GRAVY Index0.13

Hydrophobic Moment 0.83

Boman Index0.09

Instability Index39.50

Aliphatic Index 104.78

Aromaticity 0.0630

Extinction Coeff. Reduced 38390.00

Extinction Coeff. Oxidized 38640.00

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Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0059636 VERIFIED: NO

Provenance & Taxonomy

OrganismEcheneis naucrates [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria