Peptide Database

Peptide NameDefensin alpha 6

Function Ontology

Antimicrobial

Antimicrobial ▸ Antifungal

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length100 amino acids

Chemical FormulaC467H732N132O158S8

DescriptionStandard

        MRTLTFLAAILLVALQAQAEPLQAEDEPLQASAYEADAQEQRGEDNQDFTISFAADANSRITALGSTRSFTCNCRRSCYSTEYSYGTCTVMGVSNRFCCL
    

Molecular Weight10980.12 Da

Isoelectric Point (pI)4.45

Net Charge (pH 7.0)-5.54

Net Charge (pH 7.4) -5.86

Charge Density (pH 7.0) -0.0554

GRAVY Index-0.17

Hydrophobic Moment 0.57

Boman Index-0.01

Instability Index54.83

Aliphatic Index 69.50

Aromaticity 0.0900

Extinction Coeff. Reduced 5960.00

Extinction Coeff. Oxidized 6335.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 4726.59

LogP -59.19

H-bond Donors 171.0

H-bond Acceptors 161.0

Rotatable Bonds 360.0

Heavy Atoms 765.0

Ring Count 11.0

Amide Bonds 110.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0126720 VERIFIED: NO

Provenance & Taxonomy

OrganismPapio anubis [Animal]

FamilyAlpha-defensin; Defensin

Tax ID9555

Structure & Mods

Configdisulfide-constrained cyclic peptide [Cyclic]

Chiralitycanonical L-amino-acid peptide [L]

Disulfidedisulfide bond; sites not specified

Bio-Activity Profile

Function

Antimicrobial Defensin Antifungal Non-hemolytic