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MYP_083453
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Basic Information
Bombinin H-BO
Anticancer
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antifungal
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Standard
17 amino acids
C77H138N18O18
Standard
Sequence
IIGPVLGLIGKALGGLL
Physicochemical Analysis
1604.03 Da
8.75
0.76
0.55
0.0447
1.82
0.43
0.72
23.01
206.47
0.0000
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
546.15
-1.01
18.0
19.0
53.0
113.0
1.0
16.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0010756 VERIFIED: YES
Provenance & Taxonomy
Bombina orientalis [Animal]
Bombinin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Anti-Gram-positive Anti-Gram-negative
Candida albicans
256 μg/mL
MIC
PMID28636781 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/28636781/
RECORD: Rec_0115964 VERIFIED: YES
Provenance & Taxonomy
Bombina orientalis [Animal]
Bombinin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Bio-Activity Profile
Hemolytic
human red blood cells
256 μg/mL
Hemolysis
PMID28636781 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/28636781/
RECORD: Rec_0141660 VERIFIED: YES
Provenance & Taxonomy
skin secretion of Oriental fire-bellied toad,Bombina orientalis [Animal]
Bombinin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial Anticancer Cytotoxic
PaperPubMed PMID: 28636781 PMID28636781 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/28636781/
RECORD: Rec_0182229 VERIFIED: YES
Provenance & Taxonomy
skin secretion of Oriental fire-bellied toad,Bombina orientalis [Animal]
Bombinin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial Anticancer
Huh-7
1.81 μM
IC50
PaperPubMed PMID: 28636781 PMID28636781 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/28636781/
RECORD: Rec_0185282 VERIFIED: YES
Provenance & Taxonomy
Bombina orientalis [Animal]
Bombinin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive
Staphylococcus aureus
256 μg/mL
MIC
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