Peptide Database

Peptide NameHepcidin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length92 amino acids

Chemical FormulaC432H688N120O131S14

DescriptionStandard

        MKTFSVAVAVAVVLAIICIQESSAFTFTGVQELEELMSNDNPVAEHEETAVDSWMMPYNFRQKRQSGPAAKKCRLCCNCCSGMRGCGVCCKF
    

Molecular Weight10107.72 Da

Isoelectric Point (pI)6.53

Net Charge (pH 7.0)-0.49

Net Charge (pH 7.4) -0.91

Charge Density (pH 7.0) -0.0053

GRAVY Index0.12

Hydrophobic Moment 0.54

Boman Index0.07

Instability Index51.26

Aliphatic Index 67.83

Aromaticity 0.0761

Extinction Coeff. Reduced 6990.00

Extinction Coeff. Oxidized 7490.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 4030.40

LogP -43.68

H-bond Donors 147.0

H-bond Acceptors 146.0

Rotatable Bonds 335.0

Heavy Atoms 697.0

Ring Count 12.0

Amide Bonds 99.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0185380 VERIFIED: NO

Provenance & Taxonomy

OrganismLates calcarifer [Bacterium]

FamilyHepcidin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibiotic Non-hemolytic Non-ribosomal