Peptide Database

Peptide NameBeta-defensin 1TB

Function Ontology

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Standard StatusStandard

Sequence Length35 amino acids

Chemical FormulaC167H261N51O49S6

DescriptionStandard

        DHYKCVRNGGTCHFSSCPLYTKIQGTCYSKRAKCC
    

Molecular Weight3959.56 Da

Isoelectric Point (pI)9.08

Net Charge (pH 7.0)4.87

Net Charge (pH 7.4) 4.47

Charge Density (pH 7.0) 0.1391

GRAVY Index-0.59

Hydrophobic Moment 0.47

Boman Index-0.16

Instability Index49.15

Aliphatic Index 33.43

Aromaticity 0.1143

Extinction Coeff. Reduced 4470.00

Extinction Coeff. Oxidized 4845.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1634.72

LogP -20.57

H-bond Donors 65.0

H-bond Acceptors 62.0

Rotatable Bonds 128.0

Heavy Atoms 273.0

Ring Count 7.0

Amide Bonds 36.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0289304 VERIFIED: YES

Provenance & Taxonomy

OrganismGaleopterus variegatus [Animal]

FamilyDefensin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

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TargetEscherichia coli TOP10

MethodMex pooled growth assay (OD_ID at 4.5 h; Wald adjusted p-value)