MYP_083437
Basic Information
[desPheol] alamethicin F30
Anticancer Cytotoxic anticancer activity Cytotoxic
Antimicrobial
Toxicity / Safety Blood cell toxicity Hemolysis Hemolytic
Toxicity / Safety Cytolysis / cell lysis Cytolytic activity
Toxicity / Safety Cytotoxicity Cytotoxic
Venom / Toxin General toxin Cytotoxic
Venom / Toxin General toxin Toxic
not Standard
19 amino acids
-
contains X representing unresolved or non-standard residue
Sequence
XPXAXAQXVXGLXPVXXEQ
Physicochemical Analysis
0.00 Da
0.00
0.00
0.00
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0073643 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
alamethicin
Structure & Mods
linear peptide [Linear]
noncanonical stereochemical modification [Modified]
Acetylation
Non-proteinogenic/modified monomers: Ac-Aib; Aib
Bio-Activity Profile
Antimicrobial
RECORD: Rec_0114567 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Acetylation
Pheol
Aib = α- methylalanine
Bio-Activity Profile
Cytolytic
Human erythrocytes
30 μM
EC50
RECORD: Rec_0288766 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
mixed L/D amino-acid peptide [Mixed]
Acetylation
Pheol
Aib = α- methylalanine
Bio-Activity Profile
Toxic Hemolytic Cytotoxic