‹ ›
MYP_083434
← PREVIOUS NEXT → BACK
Basic Information
H3
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Standard
40 amino acids
C191H285N55O54S6
Standard
Sequence
GFGCNGPWNEDDLRCHNKCKSIKGYKGGYCAKGGFVCKCY
Physicochemical Analysis
4408.03 Da
8.84
3.78
3.43
0.0946
-0.69
0.36
-0.08
31.41
29.25
0.1500
9970.00
10345.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1774.01
-19.30
67.0
65.0
145.0
306.0
9.0
42.0
Structural Visualization
3D PDB MODEL
Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.
2D CHEMICAL STRUCTURE
Drag to move
Drag to move. Use the buttons to zoom.
Experimental Records
RECORD: Rec_0035280 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Defensin
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive
Staphylococcus aureus ATCC 6538
0.114 μM
MIC
PMID28229435 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/28229435/
RECORD: Rec_0099046 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Defensin
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Hemolytic
RBC
14.55 μM
Hemolysis
PMID28229435 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/28229435/
RECORD: Rec_0117906 VERIFIED: YES
Provenance & Taxonomy
Synthetic construct [Synthetic]
Plectasin
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
S-pullorum CVCC1789
>7.273 μM
MIC
PaperDesign and pharmacodynamics of recombinant NZ2114 histidine mutants with improved activity against methicillin-resistant Staphylococcus aureus.
RECORD: Rec_0143611 VERIFIED: YES
Provenance & Taxonomy
Synthetic construct [Synthetic]
Plectasin
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
S-typhimurium ATCC 14028
>7.273 μM
MIC
PaperDesign and pharmacodynamics of recombinant NZ2114 histidine mutants with improved activity against methicillin-resistant Staphylococcus aureus.
RECORD: Rec_0158583 VERIFIED: YES
Provenance & Taxonomy
Synthetic construct [Synthetic]
Plectasin
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
S. suis CVCC3309 or CVCC3928 or CVCC606
0.014-0.028 μM
MIC
PaperDesign and pharmacodynamics of recombinant NZ2114 histidine mutants with improved activity against methicillin-resistant Staphylococcus aureus.
1 2 3 4 NEXT LAST
Showing 5 records on this page · Page 1 of 4