Peptide Database

Peptide NamePotassium channel toxin alpha-KTx 3.17

Function Ontology

Venom / Toxin ▸ General toxin ▸ Toxin

Standard StatusStandard

Sequence Length38 amino acids

Chemical FormulaC173H295N57O48S7

DescriptionStandard

        GVPINVKCSGSRDCLEPCKKAGMRFGKCINRKCHCTPK
    

Molecular Weight4166.00 Da

Isoelectric Point (pI)9.50

Net Charge (pH 7.0)6.79

Net Charge (pH 7.4) 6.43

Charge Density (pH 7.0) 0.1786

GRAVY Index-0.53

Hydrophobic Moment 0.78

Boman Index-0.21

Instability Index40.21

Aliphatic Index 48.68

Aromaticity 0.0263

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 375.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1705.62

LogP -20.59

H-bond Donors 65.0

H-bond Acceptors 63.0

Rotatable Bonds 141.0

Heavy Atoms 285.0

Ring Count 5.0

Amide Bonds 39.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0187118 VERIFIED: YES

Provenance & Taxonomy

OrganismButhus occitanus [Animal]

Structure & Mods

Configlinear disulfide-stabilized peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Disulfide8-28, 14-33, 18-35

Bio-Activity Profile

Function

Toxin

TargetRat brain synaptosomes

Activity0.0001 μM

MethodIC50