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MYP_083243
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Basic Information
ISGCock_Contig13_3006
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antibiotic activity
Antimicrobial ▸ Antifungal
Antimicrobial ▸ Antifungal ▸ Anti-Candida
Antimicrobial ▸ Antifungal ▸ Fungicidal activity
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic
Standard
13 amino acids
C70H109N19O16S
Standard
Sequence
LRHKVYGYCVLGP
Physicochemical Analysis
1504.80 Da
9.20
1.83
1.56
0.1411
0.15
0.16
0.13
25.88
104.62
0.1538
2980.00
2980.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
560.79
-2.43
21.0
20.0
45.0
106.0
4.0
12.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0084988 VERIFIED: YES
Provenance & Taxonomy
Periplaneta americana [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Bio-Activity Profile
Antimicrobial Antifungal
Aspergillus fumigatus KCTC 6145
5 μM
MIC
PMID30962256 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/30962256/
RECORD: Rec_0132940 VERIFIED: YES
Provenance & Taxonomy
Periplaneta americana [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal
Candida albicans
64 μg/mL
MIC
RECORD: Rec_0161493 VERIFIED: YES
Provenance & Taxonomy
Periplaneta americana [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Bio-Activity Profile
Antimicrobial Antifungal
Aspergillus flavus KCTC 6905
10 μM
MIC
PMID30962256 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/30962256/
RECORD: Rec_0192946 VERIFIED: NO
Provenance & Taxonomy
Periplaneta americana [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antibiotic Antimicrobial Antifungal Fungicide Anti-Candida Anti-Gram-negative Anti-Gram-positive Signal peptide Non-hemolytic Non-ribosomal
Aspergillus flavus, Aspergillus fumigatus, Candida albicans, Candida parapsilosis, Escherichia coli, Malassezia furfur, Staphylococcus aureus, Trichosporon beigelii
Qualitative functional evidence
PMID28949065 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/28949065/; https://www.uniprot.org/uniprotkb/C0HLK9/entry; https://bblserver.org.in/ampdb/
RECORD: Rec_0286646 VERIFIED: YES
Provenance & Taxonomy
Periplaneta americana [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Bio-Activity Profile
Hemolytic
Human erythrocytes [0% percent hemolysis at 80microM]
80 μM
Hemolysis
PMID30962256 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/30962256/
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