Peptide Database

Peptide NameBeta-defensin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Standard StatusStandard

Sequence Length69 amino acids

Chemical FormulaC367H588N106O92S8

DescriptionStandard

        MRLLHSILGVLALLSIVPQARTSFFKDICSSKRYHCRMKCNPDEHAIKYCADWTICCKPKRIQFREKKW
    

Molecular Weight8213.77 Da

Isoelectric Point (pI)9.65

Net Charge (pH 7.0)8.70

Net Charge (pH 7.4) 8.23

Charge Density (pH 7.0) 0.1261

GRAVY Index-0.26

Hydrophobic Moment 0.57

Boman Index-0.10

Instability Index17.24

Aliphatic Index 82.03

Aromaticity 0.1014

Extinction Coeff. Reduced 13980.00

Extinction Coeff. Oxidized 14355.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3210.77

LogP -24.59

H-bond Donors 121.0

H-bond Acceptors 112.0

Rotatable Bonds 275.0

Heavy Atoms 573.0

Ring Count 15.0

Amide Bonds 71.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0228541 VERIFIED: NO

Provenance & Taxonomy

OrganismPanthera leo [Animal]

FamilyDefensin

Structure & Mods

Configdisulfide-stabilized peptide with linear backbone [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Defensin

MethodQualitative functional evidence