Peptide Database

Peptide NameNeurotrophin-3

Function Ontology

Immunology ▸ Immune modulation ▸ Cytokine modulation

Regulatory peptide ▸ Cell signaling / Growth factor signaling ▸ Growth factor activity

Standard StatusStandard

Sequence Length119 amino acids

Chemical FormulaC589H934N180O181S6

DescriptionStandard

        YAEHKSHRGEYSVCDSESLWVTDKSSAIDIRGHQVTVLGEIKTGNSPVKQYFYETRCKEARPVKNGCRGIDDKHWNSQCKTSQTYVRALTSENNKLVGWRWIRIDTSCVCALSRKIGRT
    

Molecular Weight13625.20 Da

Isoelectric Point (pI)9.24

Net Charge (pH 7.0)7.06

Net Charge (pH 7.4) 6.53

Charge Density (pH 7.0) 0.0593

GRAVY Index-0.77

Hydrophobic Moment 0.88

Boman Index-0.19

Instability Index37.94

Aliphatic Index 65.46

Aromaticity 0.0840

Extinction Coeff. Reduced 29450.00

Extinction Coeff. Oxidized 29825.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 5935.31

LogP -68.85

H-bond Donors 220.0

H-bond Acceptors 198.0

Rotatable Bonds 458.0

Heavy Atoms 956.0

Ring Count 20.0

Amide Bonds 127.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0139291 VERIFIED: YES

Provenance & Taxonomy

OrganismHomo sapiens [Animal]

FamilyNGF-beta family

Tax ID9606; 0

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Disulfide14-79; 57-108; 67-110

Bio-Activity Profile

Function

Cytokine Growth factor NGF-beta family Chemoattractant Growth factor signaling