Peptide Database

Peptide NameTolA protein

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Enzyme / Catalytic activity ▸ Hydrolase

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length565 amino acids

Chemical FormulaC2583H4169N747O820S12

DescriptionStandard

        MADNALNTAKNKRKEAIDAVPVATQAEKKYQDLQQSIKGLTLNNNGQYGTQKWEVISSNKEHDHWGYRFYPSGITKAQVDAAQNDAVNKRNAATSLASQATAAEQASLQASAAYNAAETRRQAAQAALASAEQAAAAERKRQEAEAAAAAAAEKKRQADAAAKAAEEARAIAEKAKALQARCTAADKLKSSEIQAVRGIPATAAPFAIPLTWSTASRGGFTLSADAAASLGAFISEALATLSIAVVANPVALTIVGLVLSKSVGVGSDMVPGRDISSMMPGDAFGLPDTAALNKAADQKTSVSMPVRGRLVMNDSGILDVQLVKTNTAGAVKVARAVLDKETGYWGYTLPAVADVPAQTIFVSPADALGANGPLTLSGPVPLPERILHTGDQISAPQATDKTVTPVADDLDFDDIILVFPPESGLKPLYVMYRSPRNMPGTVSGKGQNVGNNWMGGASTGDGAPVPSQIADKLRGKTFGSFDSTRRAFWKAVADDSALSKQFSEADINQMKAGRAPTADFLESVGKRVKIELHHEKEISQGGAVMDVDNIKALTPKNHIETHKGK
    

Molecular Weight59193.03 Da

Isoelectric Point (pI)8.58

Net Charge (pH 7.0)3.16

Net Charge (pH 7.4) 2.44

Charge Density (pH 7.0) 0.0056

GRAVY Index-0.26

Hydrophobic Moment 0.63

Boman Index0.01

Instability Index37.54

Aliphatic Index 80.35

Aromaticity 0.0496

Extinction Coeff. Reduced 46410.00

Extinction Coeff. Oxidized 46410.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0026139 VERIFIED: YES

Provenance & Taxonomy

OrganismKlebsiella pneumoniae [Bacterium]

FamilyPyocin

Structure & Mods

Configlinear polypeptide/propeptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Anti-Gram-negative Antibiotic Bacteriocin Hydrolase Non-hemolytic Non-ribosomal

TargetEscherichia coli