Peptide Database

Peptide NamePro-melanin concentrating hormone [ 110-123]

Function Ontology

Cardiovascular

Hormonal / Endocrine ▸ Hormone peptide

Metabolic ▸ Appetite and feeding regulation ▸ Feeding regulator

Neurological / Signaling ▸ Neuromodulation

Neurological / Signaling ▸ Neuropeptide activity ▸ Neuropeptide

Neurological / Signaling ▸ Sleep regulation

Regulatory peptide ▸ Biological modulation

Regulatory peptide ▸ Biological regulation

Standard StatusStandard

Sequence Length14 amino acids

Chemical FormulaC65H100N16O25

DescriptionStandard

        EIGDEENSAKFPIG
    

Molecular Weight1505.58 Da

Isoelectric Point (pI)4.05

Net Charge (pH 7.0)-3.16

Net Charge (pH 7.4) -3.33

Charge Density (pH 7.0) -0.2255

GRAVY Index-0.79

Hydrophobic Moment 0.15

Boman Index0.01

Instability Index60.09

Aliphatic Index 62.86

Aromaticity 0.0714

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 0.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 671.37

LogP -7.11

H-bond Donors 21.0

H-bond Acceptors 22.0

Rotatable Bonds 50.0

Heavy Atoms 106.0

Ring Count 2.0

Amide Bonds 14.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0420543 VERIFIED: YES

Provenance & Taxonomy

Organismnot reported [other]

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Neuropeptide

Paper数据库级溯源文献：Wang Y, Wang M, Yin S, et al. NeuroPep: a comprehensive resource of neuropeptides. Database (Oxford). 2015:bav038. PMID 25931458; Bin Y, Zhang W, Tang W, et al. Prediction of Neuropeptides from Sequence Information Using Ensemble Classifier and Hybrid Features. J Proteome Res. 2020;19(9):3732-3740. PMID 32786686. PMID25931458;32786686 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/25931458/

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