Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length198 amino acids

Chemical FormulaC962H1513N267O262S9

DescriptionStandard

        PAALPAAHEPMLLLAVTEFVANSAAFTYFTAGALRRNLSSDMVPRRFPLQLRTKSLGLFSPQLQELFPDQPMELHLSARRQPQLSCRPDALHGAIFGSAEAFVVLPNATRVPAFLLNIDANVTGKPTITGNRLGGTVRLMGVWGCCGDPVLGQCCRVPAQGWQGAELGLGGLPVPQVERLETALKFGLWLFGVPWANS
    

Molecular Weight21299.52 Da

Isoelectric Point (pI)8.82

Net Charge (pH 7.0)3.19

Net Charge (pH 7.4) 2.89

Charge Density (pH 7.0) 0.0161

GRAVY Index0.17

Hydrophobic Moment 0.57

Boman Index0.15

Instability Index50.38

Aliphatic Index 94.65

Aromaticity 0.0808

Extinction Coeff. Reduced 23490.00

Extinction Coeff. Oxidized 23740.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 8286.59

LogP -100.14

H-bond Donors 286.0

H-bond Acceptors 277.0

Rotatable Bonds 672.0

Heavy Atoms 1500.0

Ring Count 41.0

Amide Bonds 214.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0326476 VERIFIED: NO

Provenance & Taxonomy

OrganismCiccaba nigrolineata [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria