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MYP_083096
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Basic Information
Dermaseptin-like peptide (SmDLP; Frogs, amphibians, animals)
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antibiotic activity
Antimicrobial ▸ Antifungal
Antimicrobial ▸ Antifungal ▸ Anti-Candida
Antimicrobial ▸ Antifungal ▸ Fungicidal activity
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytolysis / cell lysis ▸ Cytolytic activity
Standard
27 amino acids
C118H194N36O38S2
Standard
Sequence
DLWNSIKDMAAAAGRAALNAVTGMVNQ
Physicochemical Analysis
2789.15 Da
5.96
-0.24
-0.44
-0.0088
0.16
0.55
0.14
15.31
90.74
0.0370
5500.00
5500.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1211.05
-14.31
41.0
40.0
92.0
194.0
2.0
30.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0196186 VERIFIED: NO
Provenance & Taxonomy
Schistosoma mansoni [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antibiotic Antimicrobial Antifungal Fungicide Anti-Candida Anti-Gram-negative Cytolytic Hemolytic Non-ribosomal
Micrococcus luteus
Qualitative functional evidence
PMID16539015 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/16539015/; https://www.uniprot.org/uniprotkb/P83914/entry; https://bblserver.org.in/ampdb/
RECORD: Rec_0228433 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antibacterial Antimicrobial Antifungal
PaperYADAMP: yet another database of antimicrobial peptides PMID22325123 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/22325123/
RECORD: Rec_0303808 VERIFIED: NO
Provenance & Taxonomy
Schistosoma mansoni [Animal]
Dermaseptin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal
Micrococcus luteus
RECORD: Rec_0389065 VERIFIED: NO
Provenance & Taxonomy
Schistosoma mansoni [Animal]
Dermaseptin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
PaperJ Parasitol. 2005 Dec;91(6):1340-51. | http://www.ncbi.nlm.nih.gov/pubmed/16539015 PMID16539015 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/16539015/
RECORD: Rec_0395135 VERIFIED: YES
Provenance & Taxonomy
Schistosoma mansoni [Animal]
Dermaseptin
Structure & Mods
Single-chain peptide backbone represented as a linear sequence entry [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Anti-Gram-positive
Micrococcus luteus
PMID16539015 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/16539015/
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