Peptide Database

Peptide NameDefensin SD2 (Flower-specific gamma-thionin)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial

Antimicrobial ▸ Antifungal

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length78 amino acids

Chemical FormulaC362H591N111O105S14

DescriptionStandard

        MKSSMKMFAALLLVVMCLLANEMGGPLVVEARTCESQSHKFKGTCLSDTNCANVCHSERFSGGKCRGFRRRCFCTTHC
    

Molecular Weight8627.16 Da

Isoelectric Point (pI)9.01

Net Charge (pH 7.0)5.68

Net Charge (pH 7.4) 5.17

Charge Density (pH 7.0) 0.0728

GRAVY Index0.02

Hydrophobic Moment 0.56

Boman Index-0.02

Instability Index53.24

Aliphatic Index 60.00

Aromaticity 0.0641

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 500.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3484.39

LogP -41.13

H-bond Donors 134.0

H-bond Acceptors 128.0

Rotatable Bonds 292.0

Heavy Atoms 592.0

Ring Count 9.0

Amide Bonds 81.0

3D PDB MODEL

Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.

2D CHEMICAL STRUCTURE

Drag to move

Drag to move. Use the buttons to zoom.

RECORD: Rec_0270966 VERIFIED: NO

Provenance & Taxonomy

OrganismHelianthus annuus [Animal]

FamilyDefensin; Thionin

Structure & Mods

Configdisulfide-constrained cyclic peptide [Cyclic]

Chiralitycanonical L-amino-acid peptide [L]

Disulfidedisulfide bond; sites not specified

Bio-Activity Profile

Function

Antimicrobial Antifungal Non-hemolytic

RECORD: Rec_0395110 VERIFIED: NO

Provenance & Taxonomy

OrganismHelianthus annuus [Plant]

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibacterial Antifungal