Peptide Database

Peptide NameDefensin beta 11

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length77 amino acids

Chemical FormulaC382H608N102O103S12

DescriptionStandard

        MRTLCSLLLICCLLFSYTTPAVGDLKHLILKAQLTRCYKFGGFCYNSMCPPHTKLIGNCHPDHLHCCINMKELEGST
    

Molecular Weight8662.32 Da

Isoelectric Point (pI)8.41

Net Charge (pH 7.0)2.85

Net Charge (pH 7.4) 2.23

Charge Density (pH 7.0) 0.0370

GRAVY Index0.25

Hydrophobic Moment 0.43

Boman Index0.15

Instability Index17.91

Aliphatic Index 92.47

Aromaticity 0.0779

Extinction Coeff. Reduced 4470.00

Extinction Coeff. Oxidized 4970.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3221.61

LogP -27.07

H-bond Donors 120.0

H-bond Acceptors 123.0

Rotatable Bonds 281.0

Heavy Atoms 599.0

Ring Count 15.0

Amide Bonds 80.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0174582 VERIFIED: NO

Provenance & Taxonomy

OrganismMus spicilegus [Animal]

FamilyDefensin

Tax ID10103

Structure & Mods

Configgene-encoded linear polypeptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Defensin Non-hemolytic Non-ribosomal