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MYP_083062
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Basic Information
Peptide 4
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Sensory / Food function ▸ Taste-active peptide ▸ Bitter peptide
Standard
1 amino acids
C9H11NO2
Standard
Sequence
F
Physicochemical Analysis
165.19 Da
5.53
-0.24
-0.44
-0.2399
2.80
1.19
1.19
0.00
0.00
1.0000
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
63.32
0.64
2.0
2.0
3.0
12.0
1.0
0.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0014276 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Defensin
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive
Staphylococcus aureus
500 μg/mL
MIC
PMID7972024 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/7972024/
RECORD: Rec_0060097 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Amino acid
32630
Structure & Mods
linear contiguous peptide sequence [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Bitter
0.05 Rcaf
Relative bitterness (Rcaf)
PaperStudies on a model bitter peptides including arginine, proline and phenylalanine residues. I. Bitter taste of di- and tripeptides and bitterness increase of the model peptides by extension of the peptide chain. Agric. Biol. Chem., 49, 1019-1026, 1985
RECORD: Rec_0101813 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Defensin
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive
S. sanguis
500 μg/mL
MIC
PMID7972024 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/7972024/
RECORD: Rec_0250767 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
-
Escherichia coli TOP10
Mex pooled growth assay (OD_ID at 4.5 h; Wald adjusted p-value)
PaperKoch P, Schmitt S, Cardner M, Beerenwinkel N, Panke S, Held M. Discovery of antimicrobials by massively parallelized growth assays (Mex). Scientific Reports. 2022;12:4097. doi:10.1038/s41598-022-07755-7 PMID35260685 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/35260685/
RECORD: Rec_0265262 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
N-acyl amino acid
32630
Structure & Mods
linear contiguous peptide sequence [Linear]
Name/InChI indicate an N-acetyl-L-amino acid with retained natural stereocenter [L]
Acetylation
N-acetylated amino acid
Bio-Activity Profile
Kokumi
PaperDiscovery of a thiamine-derived taste enhancer in process flavors. J. Agric. Food Chem., 67, 5857-5865, 2019 PMID31038935 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/31038935/