Peptide Database

Peptide NameType VI secretion system effector; Hcp1 family

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Enzyme / Catalytic activity ▸ Hydrolase

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length588 amino acids

Chemical FormulaC2930H4492N804O875S13

DescriptionStandard

        MSNIIYLRITGERQGNISADCGSEASIGNRWQQNHTDEIFAFSLRHDVTNTGRGCHFQALEFTKTIDKSSPLLSNAINNNERLFIEIEFYRINRTGHWERYYYIQLRNASVSKIDTDINIKRLPYEHISVIYDYILCKHLITNTEYSYLNIPAEYNNLFFPQLKTSVLKVPLNNDEIKTPPPAPEKVTPVYAKSCLKEPGCTDAGDTEEPAEHFGEMAIFARTDVDDCCGYDHKPASKHSAVPAEASSVVLALPVAMNWVWGSKSLGGLLGAAESVPWIGALASALYIPAAGEGSARVPGRDEYWYDDILRQKAAVGGTATTRVRFFWRNDIHGNPQVYGVHTGEGTPYENVRVANMVWNATTGRYEFTPANGVDGPLITWTPEHPESGNAPGHTGNNVPTLDQPTILVTPIPDGKDGYTTPPYPVPDITDFNDYILVFPAGSGIKPIYVYLKTARDEPGVATGNGQVIPDNVRWLEAASSGIGAPIPAQVADKLRGREFRDFNHFRKELWRAVSECPELLSQLKASNQSIVKIKGSPYVIPEQAVGGREVFELHHLKQIQHDGPVYDMDNLRVNTPLNHIRIHKEAE
    

Molecular Weight65396.72 Da

Isoelectric Point (pI)5.71

Net Charge (pH 7.0)-13.83

Net Charge (pH 7.4) -15.28

Charge Density (pH 7.0) -0.0235

GRAVY Index-0.40

Hydrophobic Moment 0.66

Boman Index0.02

Instability Index37.40

Aliphatic Index 80.78

Aromaticity 0.0952

Extinction Coeff. Reduced 99240.00

Extinction Coeff. Oxidized 99740.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0058821 VERIFIED: YES

Provenance & Taxonomy

OrganismEnterobacteriaceae bacterium [Bacterium]

Tax ID1849603

Structure & Mods

Configgene-encoded linear polypeptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Bacteriocin Anti-Gram-negative Hydrolase Non-hemolytic Non-ribosomal

TargetEscherichia coli