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MYP_083022
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Basic Information
Uperin 3.6
Anticancer
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antiviral
Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic
Standard
17 amino acids
C85H146N22O22
Standard
Sequence
GVIDAAKKVVNVLKNLF
Physicochemical Analysis
1828.20 Da
9.70
1.76
1.55
0.1034
0.75
0.71
0.22
-0.58
148.82
0.0588
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
730.46
-4.56
24.0
24.0
63.0
129.0
1.0
18.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0381645 VERIFIED: YES
Provenance & Taxonomy
Floodplain toadlet [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antiviral
Pasteurella multocida
>100 μg/mL
MIC
PaperNew antibiotic uperin peptides from the dorsal glands of the australian toadlet Uperoleia mjobergii.
RECORD: Rec_0382421 VERIFIED: YES
Provenance & Taxonomy
Uperoleia mjobergii [Animal]
Uperin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
PMID10461748 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/10461748/
RECORD: Rec_0389798 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Antiviral Anti-Gram-positive Anti-Gram-negative
PaperAPD2: the updated antimicrobial peptide database and its application in peptide design PMID18957441 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/18957441/
RECORD: Rec_0408035 VERIFIED: NO
Provenance & Taxonomy
Uperoleia mjobergii [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Anti-Gram-negative Anti-Gram-positive Non-hemolytic
Lactococcus lactis
Evidence URLhttps://www.uniprot.org/uniprotkb/P82043/entry
RECORD: Rec_0412613 VERIFIED: YES
Provenance & Taxonomy
Uperoleia mjobergii [Animal]
Uperin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Leuconostoc lactis
3 μg/mL
MIC
PMID10461748 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/10461748/
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