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MYP_083022
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Basic Information
Uperin 3.6
Anticancer
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antiviral
Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic
Standard
17 amino acids
C85H146N22O22
Standard
Sequence
GVIDAAKKVVNVLKNLF
Physicochemical Analysis
1828.20 Da
9.70
1.76
1.55
0.1034
0.75
0.71
0.22
-0.58
148.82
0.0588
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
730.46
-4.56
24.0
24.0
63.0
129.0
1.0
18.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0273733 VERIFIED: YES
Provenance & Taxonomy
Floodplain toadlet [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antiviral
Lactococcus lactis
3 μg/mL
MIC
PaperNew antibiotic uperin peptides from the dorsal glands of the australian toadlet Uperoleia mjobergii.
RECORD: Rec_0275287 VERIFIED: YES
Provenance & Taxonomy
Uperoleia mjobergii [Animal]
Uperin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Leuconostoc lactis
3 μg/mL
MIC
PMID10461748 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/10461748/
RECORD: Rec_0278327 VERIFIED: YES
Provenance & Taxonomy
Floodplain toadlet [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antiviral
Staphylococcus aureus
25 μg/mL
MIC
PaperNew antibiotic uperin peptides from the dorsal glands of the australian toadlet Uperoleia mjobergii.
RECORD: Rec_0293542 VERIFIED: NO
Provenance & Taxonomy
Uperoleia mjobergii [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Anti-Gram-negative Anti-Gram-positive Non-hemolytic
Staphylococcus aureus
Evidence URLhttps://www.uniprot.org/uniprotkb/P82043/entry
RECORD: Rec_0313676 VERIFIED: YES
Provenance & Taxonomy
Litoria aurea; Litoria raniformis [Animal]
Aurein
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial
PaperRozek T., Wegener K., Bowie J., Olver I. N., Carver J. A., Wallace J. C., Tyler M. J.. The antibiotic and anticancer active aurein peptides from the Australian Bell Frogs Litoria aurea and Litoria raniformis. Eur. J. Biochem, 267, 5330-5341. PMID10951191 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/10951191/
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