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MYP_083016
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Basic Information
Phenol-soluble modulin alpha 1 peptide (6-21), PSMalpha1 (6-21)
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Immunology ▸ Immunomodulation ▸ Immunosuppressive
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Venom / Toxin ▸ General toxin ▸ Toxic
Standard
16 amino acids
C83H144N20O22
Standard
Sequence
GIIKVIKSLIEQFTGK
Physicochemical Analysis
1774.15 Da
9.70
1.76
1.55
0.1100
0.49
0.71
0.22
12.32
140.00
0.0625
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
698.73
-4.05
24.0
24.0
64.0
125.0
1.0
16.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0208301 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial
Staphylococcus aureus USA 300
64 μM
MIC
PMID22371493 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/22371493/
RECORD: Rec_0239277 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide; DSSP H 81.2%, E 0.0%, T 6.2%, C 12.5% [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Toxic Antimicrobial Hemolytic Immunosuppressive
PaperHemolytik: a database of experimentally determined hemolytic and non-hemolytic peptides PMID24174543 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/24174543/
RECORD: Rec_0263270 VERIFIED: YES
Provenance & Taxonomy
Truncated the [Bacterium]
Bacteriocin
Structure & Mods
topology not specified [Not included yet]
stereochemistry not specified [Other]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive
human red blood cells
PMID22371493 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/22371493/
RECORD: Rec_0380752 VERIFIED: YES
Provenance & Taxonomy
Truncated the [Bacterium]
Bacteriocin
Structure & Mods
topology not specified [Not included yet]
stereochemistry not specified [Other]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive
Streptococcus serotype GAS M3 strain 4041-05
11 μM
MIC
PMID22371493 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/22371493/
RECORD: Rec_0405464 VERIFIED: YES
Provenance & Taxonomy
Truncated the [Bacterium]
Bacteriocin
Structure & Mods
topology not specified [Not included yet]
stereochemistry not specified [Other]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive
PMID22371493 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/22371493/
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