Peptide Database

Peptide NameChicken LEAP-2

Function Ontology

Antimicrobial

Standard StatusStandard

Sequence Length40 amino acids

Chemical FormulaC193H316N62O56S6

DescriptionStandard

        MTPFWRGVSLRPIGASCRDNSECITMLCRKNRCFLRSASE
    

Molecular Weight4593.35 Da

Isoelectric Point (pI)9.37

Net Charge (pH 7.0)3.47

Net Charge (pH 7.4) 3.19

Charge Density (pH 7.0) 0.0868

GRAVY Index-0.28

Hydrophobic Moment 0.70

Boman Index-0.16

Instability Index63.80

Aliphatic Index 61.00

Aromaticity 0.0750

Extinction Coeff. Reduced 5500.00

Extinction Coeff. Oxidized 5750.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1933.54

LogP -22.67

H-bond Donors 75.0

H-bond Acceptors 66.0

Rotatable Bonds 151.0

Heavy Atoms 317.0

Ring Count 6.0

Amide Bonds 41.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0156843 VERIFIED: YES

Provenance & Taxonomy

OrganismAnser cygnoides [Animal]

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibacterial

TargetEscherichia coli TOP10

MethodMex pooled growth assay (OD_ID at 4.5 h; Wald adjusted p-value)

RECORD: Rec_0362059 VERIFIED: YES