Peptide Database

Peptide NameBeta-defensin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length73 amino acids

Chemical FormulaC371H594N106O99S9

DescriptionStandard

        MRIPVLLFTIFFFMSQVLPARGKFKEICERPNGSCRDFCLKTEIHVGRCLNSRPCCLPLGHQPRIESTTPQMD
    

Molecular Weight8411.92 Da

Isoelectric Point (pI)8.93

Net Charge (pH 7.0)3.63

Net Charge (pH 7.4) 3.21

Charge Density (pH 7.0) 0.0497

GRAVY Index-0.08

Hydrophobic Moment 0.47

Boman Index-0.01

Instability Index58.58

Aliphatic Index 77.40

Aromaticity 0.0822

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 375.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3266.80

LogP -29.18

H-bond Donors 118.0

H-bond Acceptors 114.0

Rotatable Bonds 273.0

Heavy Atoms 585.0

Ring Count 15.0

Amide Bonds 77.0

3D PDB MODEL

Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.

2D CHEMICAL STRUCTURE

Drag to move

Drag to move. Use the buttons to zoom.

RECORD: Rec_0327577 VERIFIED: NO

Provenance & Taxonomy

OrganismCercocebus atys [Animal]

FamilyDefensin

Tax ID9531

Structure & Mods

Configlinear polypeptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Defensin Non-hemolytic

MethodQualitative functional evidence