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MYP_082982
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Basic Information
Hyfl C
Antimicrobial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Insecticidal/Pest control ▸ Insecticidal activity
Standard
32 amino acids
C146H231N39O47S7
Standard
Sequence
GSPRQCAETCFIGKCYTEELGCTCTAFLCMKN
Physicochemical Analysis
3509.08 Da
6.19
-0.29
-0.59
-0.0092
0.02
0.32
0.05
66.19
42.81
0.0938
1490.00
1865.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1390.03
-16.46
54.0
54.0
114.0
239.0
4.0
33.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0142857 VERIFIED: YES
Provenance & Taxonomy
Pigea floribunda [Plant]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Anti-Gram-negative
Escherichia coli TOP10
Mex pooled growth assay (OD_ID at 4.5 h; Wald adjusted p-value)
PaperKoch P, Schmitt S, Cardner M, Beerenwinkel N, Panke S, Held M. Discovery of antimicrobials by massively parallelized growth assays (Mex). Scientific Reports. 2022;12:4097. doi:10.1038/s41598-022-07755-7 PMID35260685 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/35260685/
RECORD: Rec_0152822 VERIFIED: YES
Provenance & Taxonomy
Hybanthus floribundus [Plant]
Cyclotide
642016
Structure & Mods
head-to-tail cyclic peptide scaffold [Cyclic]
canonical L-amino-acid peptide [L]
Cysteine-rich scaffold consistent with multiple disulfide bonds in the annotated family
Bio-Activity Profile
Antimicrobial Insecticidal
PaperA continent of plant defense peptide diversity: cyclotides in Australian Hybanthus (Violaceae) PMID16199617 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/16199617/
RECORD: Rec_0186175 VERIFIED: YES
Provenance & Taxonomy
Hybanthus floribundus [Plant]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
-
PaperA continent of plant defense peptide diversity: cyclotides in Australian Hybanthus (Violaceae). PMID16199617 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/16199617/
RECORD: Rec_0282440 VERIFIED: NO
Provenance & Taxonomy
Hybanthus floribundus [Plant]
Cyclotide
Structure & Mods
Backbone-cyclized cyclotide scaffold with cystine-knot family annotation [Cyclic]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
Evidence URLhttps://camp.bicnirrh.res.in/seqDisp.php?id=CAMPSQ6440
RECORD: Rec_0361806 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
cyclic peptide [Cyclic]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial
PaperAPD2: the updated antimicrobial peptide database and its application in peptide design PMID18957441 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/18957441/
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